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Founded in 1995 by Dr Reto Stöcklin, Atheris Laboratories is a family owned and family driven biotechnology company. Atheris has built a unique, world-class expertise and technology platform pertaining to the identification and characterisation of biomolecules. To assist its drug discovery programs, Atheris has developed proprietary databases on animal venoms and antibiotics. Using state-of-the-art separation and analytical methods, Atheris is also a world leader in performing mass spectrometry (MS) assays on polypeptides for in vivo metabolic studies.
Selected references (ask for reprints)
- Favreau, P. and Stöcklin, R. (2009). Marine snail venoms: use and trends in receptor and channel neuropharmacology. Current Opinion in Pharmacology (COPHAR), in press.
- Biass, D., Dutertre, S., Gerbault, A., Menou, J.-L., Offord, R.E., Favreau, P. and Stöcklin, R. (2009). Comparative proteomic study of the venom of the piscivorous cone snail Conus consors. J. Proteomics, 72(2)210-218.
- Stöcklin, R., Favreau, P., Thai, R., Pflugfelder, J., Bulet, P. and Mebs, D. (2009). Structural identification by mass spectrometry of a novel antimicrobial peptide from the venom of the solitary bee Osmia rufa (Hymenoptera: Megachilidae). Toxicon, in press.
- Menin, L., Perchuc, A., Favreau, P., Perret, F., Michalet, S., Schöni, R., Wilmer, M. and Stöcklin R. (2008). High throughput screening of bradykinin-potentiating peptides in Bothrops moojeni snake venom using precursor ion mass spectrometry. Toxicon 51(7):1288-1302.
- Favreau, P., Cheneval, O., Menin, L., Michalet, S., Gaertner, H., Principaud, F., Thai, R., Ménez, A., Bulet, P. and Stöcklin, R. (2007). The venom of the snake genus Atheris contains a new class of peptides with clusters of histidine and glycine residues. Rapid Commun. Mass Spectrom. 21:406-412.
- Favreau, P., Menin, L., Michalet, S., Perret, F., Cheneval, O., Stöcklin, M., Bulet, P. and Stöcklin, R. (2006). Mass spectrometry strategies for venom mapping and peptide sequencing from crude venoms: case applications with single arthropod specimen. Toxicon 47(6):676-87.
- Ménez, A., Stöcklin, R. and Mebs, D., 2006. ‘Venomics’ or: The venomous systems genome project. Toxicon, p. 255–259.
- Stöcklin, R. and Favreau, P., 2002. Proteomics of venom peptides. In : Perspectives in molecular toxinology (Ménez A Ed.), John Wiley & Sons Ltd, Chichester, UK, p. 107-123.
More references
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